Faculty Publications

  • Kukida, M ; Cai, L.; Ye, D.; Sawada, H.; Katsumata, Y.; Franklin, MK ; Hecker, PI ; Campbell, KS ; Danser, AHJ ; Mullick, AE ; Daugherty, A.; Temel, RE ; Lu, HS Renal Angiotensinogen Is Predominantly Liver Derived in Nonhuman Primates. Arteriosclerosis, thrombosis, and vascular biology 2021 ATVBAHA121316590 [PubMed Link] | [Full Text]
  • Kukida, M ; Cai, L.; Ye, D.; Sawada, H.; Katsumata, Y.; Franklin, MK ; Hecker, PI ; Campbell, KS ; Danser, AHJ ; Mullick, AE ; Daugherty, A.; Temel, RE ; Lu, HS Renal Angiotensinogen Is Predominantly Liver Derived in Nonhuman Primates. Arteriosclerosis, thrombosis, and vascular biology 2021 ATVBAHA121316590 [PubMed Link] | [Full Text]
  • Kukida, M ; Cai, L.; Ye, D.; Sawada, H.; Katsumata, Y.; Franklin, MK ; Hecker, PI ; Campbell, KS ; Danser, AHJ ; Mullick, AE ; Daugherty, A.; Temel, RE ; Lu, HS Renal Angiotensinogen Is Predominantly Liver Derived in Nonhuman Primates. Arteriosclerosis, thrombosis, and vascular biology 2021 ATVBAHA121316590 [PubMed Link] | [Full Text]
  • Kloske, CM ; Dugan, AJ ; Weekman, EM ; Winder, Z ; Patel, E.; Nelson, PT ; Fardo, DW ; Wilcock, DM Inflammatory Pathways Are Impaired in Alzheimer Disease and Differentially Associated With Apolipoprotein E Status. Journal of neuropathology and experimental neurology 2021 [PubMed Link] | [Full Text]
  • Ahern, BM ; Sebastian, A.; Levitan, BM ; Goh, J.; Andres, DA ; Satin, J. L-type channel inactivation balances the increased peak calcium current due to absence of Rad in cardiomyocytes. The Journal of general physiology 153 9 2021 [PubMed Link] | [Full Text]
  • Ikezoe, T ; Shoji, T.; Guo, J.; Shen, F.; Lu, HS ; Daugherty, A.; Nunokawa, M ; Kubota, H ; Miyata, M ; Xu, B.; Dalman, RL No Effect of Hypercholesterolemia on Elastase-Induced Experimental Abdominal Aortic Aneurysm Progression. Biomolecules 11 10 2021 [PubMed Link] | [Full Text]
  • Ikezoe, T ; Shoji, T.; Guo, J.; Shen, F.; Lu, HS ; Daugherty, A.; Nunokawa, M ; Kubota, H ; Miyata, M ; Xu, B.; Dalman, RL No Effect of Hypercholesterolemia on Elastase-Induced Experimental Abdominal Aortic Aneurysm Progression. Biomolecules 11 10 2021 [PubMed Link] | [Full Text]
  • Rogers, MA ; Hutcheson, JD ; Okui, T ; Goettsch, C ; Singh, SA ; Halu, A ; Schlotter, F ; Higashi, H ; Wang, L.; Whelan, MC ; Mlynarchik, AK ; Daugherty, A.; Nomura, M.; Aikawa, M.; Aikawa, E Dynamin-related protein 1 inhibition reduces hepatic PCSK9 secretion. Cardiovascular research 117 11 2021 2340-2353 [PubMed Link] | [Full Text]
  • Cui, H.; Chen, Y.; Li, K.; Zhan, R.; Zhao, M.; Xu, Y.; Lin, Z.; Fu, Y.; He, Q.; Tang, PC ; Lei, I ; Zhang, J.; Li, C.; Sun, Y.; Zhang, X.; Horng, T ; Lu, HS ; Chen, YE ; Daugherty, A.; Wang, D.; Zheng, L. Untargeted metabolomics identifies succinate as a biomarker and therapeutic target in aortic aneurysm and dissection. European heart journal 2021 [PubMed Link] | [Full Text]
  • Cui, H.; Chen, Y.; Li, K.; Zhan, R.; Zhao, M.; Xu, Y.; Lin, Z.; Fu, Y.; He, Q.; Tang, PC ; Lei, I ; Zhang, J.; Li, C.; Sun, Y.; Zhang, X.; Horng, T ; Lu, HS ; Chen, YE ; Daugherty, A.; Wang, D.; Zheng, L. Untargeted metabolomics identifies succinate as a biomarker and therapeutic target in aortic aneurysm and dissection. European heart journal 2021 [PubMed Link] | [Full Text]
  • Wilcock, DM ; Schmidt, RL ; Furtado, LV ; Matynia, AP ; Deftereos, G ; Sirohi, D Histologic and Molecular Characterization of Non-Small Cell Lung Carcinoma With Discordant ROS1 Immunohistochemistry and Fluorescence In Situ Hybridization. Applied immunohistochemistry & molecular morphology : AIMM 2021 [PubMed Link] | [Full Text]
  • Daugherty, A.; Fisher, EA ; Taubman, MB ; Heistad, DD ; Fogelman, AM Forty-Year Anniversary of <i>Arteriosclerosis, Thrombosis, and Vascular Biology</i>. Arteriosclerosis, thrombosis, and vascular biology 41 9 2021 2353-2356 [PubMed Link] | [Full Text]
  • Cloyd, RA ; Koren J, 3rd ; Abisambra, JF ; Smith, BN Effects of altered tau expression on dentate granule cell excitability in mice. Experimental neurology 343 2021 113766 [PubMed Link] | [Full Text]
  • Whitehead, SN ; Bruno, A ; Burns, JM ; Carmichael, ST ; Csiszar, A.; Edwards, JD ; Elahi, FM ; Faraco, G.; Gould, DB ; Gustafson, DR ; Hachinski, V ; Rosenberg, G ; Sorond, FA ; Shih, AY ; Tse, KH ; Ungvari, Z.; Wilcock, DM ; Zuloaga, KL ; Barone, FC Expanding the horizon of research into the pathogenesis of the white matter diseases: Proceedings of the 2021 Annual Workshop of the Albert Research Institute for White Matter and Cognition. GeroScience 2021 [PubMed Link] | [Full Text]
  • Tran, K.; Tanner, BCW ; Campbell, KS Mathematical modeling of myosin, muscle contraction, and movement. Archives of biochemistry and biophysics 711 2021 108979 [PubMed Link] | [Full Text]
  • Sawada, H.; Daugherty, A.; Lu, HS From unbiased transcriptomics to understanding the molecular basis of atherosclerosis. Current opinion in lipidology 32 5 2021 328-329 [PubMed Link] | [Full Text]
  • Sawada, H.; Daugherty, A.; Lu, HS From unbiased transcriptomics to understanding the molecular basis of atherosclerosis. Current opinion in lipidology 32 5 2021 328-329 [PubMed Link] | [Full Text]
  • Chen, JZ ; Sawada, H.; Ye, D.; Katsumata, Y.; Kukida, M ; Ohno-Urabe, S ; Moorleghen, JJ ; Franklin, MK ; Howatt, DA ; Sheppard, MB ; Mullick, AE ; Lu, HS ; Daugherty, A. Deletion of AT1a (Angiotensin II Type 1a) Receptor or Inhibition of Angiotensinogen Synthesis Attenuates Thoracic Aortopathies in Fibrillin1<sup>C1041G/+</sup> Mice. Arteriosclerosis, thrombosis, and vascular biology 41 10 2021 2538-2550 [PubMed Link] | [Full Text]
  • Chen, JZ ; Sawada, H.; Ye, D.; Katsumata, Y.; Kukida, M ; Ohno-Urabe, S ; Moorleghen, JJ ; Franklin, MK ; Howatt, DA ; Sheppard, MB ; Mullick, AE ; Lu, HS ; Daugherty, A. Deletion of AT1a (Angiotensin II Type 1a) Receptor or Inhibition of Angiotensinogen Synthesis Attenuates Thoracic Aortopathies in Fibrillin1<sup>C1041G/+</sup> Mice. Arteriosclerosis, thrombosis, and vascular biology 41 10 2021 2538-2550 [PubMed Link] | [Full Text]
  • Shaw, BC ; Estus, S. Pseudogene-Mediated Gene Conversion After CRISPR-Cas9 Editing Demonstrated by Partial <i>CD33</i> Conversion with <i>SIGLEC22P</i>. The CRISPR journal 4 5 2021 699-709 [PubMed Link] | [Full Text]
  • Smith, JL ; Mudd-Martin, G.; Estus, S.; Lennie, TA ; Chung, ML TAS2R38 Haplotype Predicts 24-Hour Urinary Sodium Excretion in Patients With Heart Failure and Their Family Caregivers. The Journal of cardiovascular nursing 36 3 2021 238-244 [PubMed Link] | [Full Text]
  • Daugherty, A. Recipients of the 2021 Early Career Investigator Awards. Arteriosclerosis, thrombosis, and vascular biology 41 5 2021 1595 [PubMed Link] | [Full Text]
  • Gold, BT ; Shao, X.; Sudduth, TL ; Jicha, GA ; Wilcock, DM ; Seago, ER ; Wang, DJJ Water exchange rate across the blood-brain barrier is associated with CSF amyloid-β 42 in healthy older adults. Alzheimer's & dementia : the journal of the Alzheimer's Association 2021 [PubMed Link] | [Full Text]
  • Muniappan, L.; Okuyama, M.; Javidan, A.; Thiagarajan, D ; Jiang, W.; Moorleghen, JJ ; Yang, L.; Balakrishnan, A.; Howatt, DA ; Uchida, HA ; Saido, TC ; Subramanian, V. Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice. Arteriosclerosis, thrombosis, and vascular biology 41 5 2021 1694-1709 [PubMed Link] | [Full Text]
  • Kukida, M ; Sawada, H.; Ohno-Urabe, S ; Howatt, DA ; Moorleghen, JJ ; Poglitsch, M ; Daugherty, A.; Lu, HS Effects of Endogenous Angiotensin II on Abdominal Aortic Aneurysms and Atherosclerosis in Angiotensin II-Infused Mice. Journal of the American Heart Association 10 9 2021 e020467 [PubMed Link] | [Full Text]
  • Otaka, N ; Uchida, HA ; Okuyama, M.; Hada, Y ; Onishi, Y ; Kakio, Y.; Takeuchi, H.; Umebayashi, R.; Tanabe, K.; Subramanian, V.; Daugherty, A.; Sato, Y.; Wada, J. Vasohibin-2 Aggravates Development of Ascending Aortic Aneurysms but not Abdominal Aortic Aneurysms nor Atherosclerosis in ApoE-Deficient Mice. American journal of hypertension 34 5 2021 467-475 [PubMed Link] | [Full Text]
  • Otaka, N ; Uchida, HA ; Okuyama, M.; Hada, Y ; Onishi, Y ; Kakio, Y.; Takeuchi, H.; Umebayashi, R.; Tanabe, K.; Subramanian, V.; Daugherty, A.; Sato, Y.; Wada, J. Vasohibin-2 Aggravates Development of Ascending Aortic Aneurysms but not Abdominal Aortic Aneurysms nor Atherosclerosis in ApoE-Deficient Mice. American journal of hypertension 34 5 2021 467-475 [PubMed Link] | [Full Text]
  • Stewart, AN ; Lowe, JL ; Glaser, EP ; Mott, CA ; Shahidehpour, RK ; McFarlane, KE ; Bailey, WM ; Zhang, B.; Gensel, JC Acute inflammatory profiles differ with sex and age after spinal cord injury. Journal of neuroinflammation 18 1 2021 113 [PubMed Link] | [Full Text]
  • Sinha, GP ; Prasoon, P.; Smith, BN ; Taylor, BK Fast A-type currents shape a rapidly adapting form of delayed short latency firing of excitatory superficial dorsal horn neurons that express the neuropeptide Y Y1 receptor. The Journal of physiology 599 10 2021 2723-2750 [PubMed Link] | [Full Text]
  • Pandya, CD ; Vekaria, H.; Joseph, B.; Slone, SA ; Gensel, JC ; Sullivan, PG ; Miller, BA Hemoglobin induces oxidative stress and mitochondrial dysfunction in oligodendrocyte progenitor cells. Translational research : the journal of laboratory and clinical medicine 231 2021 13-23 [PubMed Link] | [Full Text]
  • Levitan, BM ; Ahern, BM ; Aloysius, A ; Brown, L.; Wen, Y.; Andres, DA ; Satin, J. Rad-GTPase contributes to heart rate via L-type calcium channel regulation. Journal of molecular and cellular cardiology 154 2021 60-69 [PubMed Link] | [Full Text]
  • James, BN ; Oyeniran, C ; Sturgill, JL ; Newton, J ; Martin, RK ; Bieberich, E.; Weigel, C ; Maczis, MA ; Palladino, END ; Lownik, JC ; Trudeau, JB ; Cook-Mills, JM ; Wenzel, S ; Milstien, S ; Spiegel, S. Ceramide in apoptosis and oxidative stress in allergic inflammation and asthma. The Journal of allergy and clinical immunology 147 5 2021 1936-1948.e9 [PubMed Link] | [Full Text]
  • Kopper, TJ ; Zhang, B.; Bailey, WM ; Bethel, KE ; Gensel, JC The effects of myelin on macrophage activation are phenotypic specific via cPLA<sub>2</sub> in the context of spinal cord injury inflammation. Scientific reports 11 1 2021 6341 [PubMed Link] | [Full Text]
  • Al-Darraji, A.; Donahue, RR ; Tripathi, H.; Peng, H.; Levitan, BM ; Chelvarajan, L.; Haydar, D.; Gao, E.; Henson, D.; Gensel, JC ; Feola, DJ ; Venditto, VJ ; Abdel-Latif, A. Author Correction: Liposomal delivery of azithromycin enhances its immunotherapeutic efficacy and reduces toxicity in myocardial infarction. Scientific reports 11 1 2021 6654 [PubMed Link] | [Full Text]
  • Ai, AL ; Smyth, SS Depression After Open Heart Surgery: Influences of Optimism, Sex, and Event-Related Medical Factors. The Journal of nervous and mental disease 209 3 2021 212-217 [PubMed Link] | [Full Text]
  • Gatineau, E ; Arthur, G.; Poupeau, A ; Nichols, K ; Spear, BT ; Shelman, NR ; Graf, GA ; Temel, RE ; Yiannikouris, FB The prorenin receptor and its soluble form contribute to lipid homeostasis. American journal of physiology. Endocrinology and metabolism 320 3 2021 E609-E618 [PubMed Link] | [Full Text]
  • Ito, M.; Wang, Q.; Hao, D.; Sawada, H.; Huang, B.; Guo, L.; Daugherty, A.; Li, XA Ultrasound Monitoring of Thymus Involution in Septic Mice. Ultrasound in medicine & biology 47 3 2021 769-776 [PubMed Link] | [Full Text]
  • Kopper, TJ ; Gensel, JC Continued development of azithromycin as a neuroprotective therapeutic for the treatment of spinal cord injury and other neurological conditions. Neural regeneration research 16 3 2021 508-509 [PubMed Link] | [Full Text]
  • Stewart, AN ; McFarlane, KE ; Vekaria, HJ ; Bailey, WM ; Slone, SA ; Tranthem, LA ; Zhang, B.; Patel, SP ; Sullivan, PG ; Gensel, JC Mitochondria exert age-divergent effects on recovery from spinal cord injury. Experimental neurology 337 2021 113597 [PubMed Link] | [Full Text]
  • Stewart, AN ; McFarlane, KE ; Vekaria, HJ ; Bailey, WM ; Slone, SA ; Tranthem, LA ; Zhang, B.; Patel, SP ; Sullivan, PG ; Gensel, JC Mitochondria exert age-divergent effects on recovery from spinal cord injury. Experimental neurology 337 2021 113597 [PubMed Link] | [Full Text]
  • Smyth, S.; Gupta, V.; Williams, M.; Cowley, A ; Sirrine, M ; Surratt, H ; Chadha, R.; Stearley, S ; Bhalla, V ; Li, J. Identifying Guideline-Practice Gaps to Optimize Evaluation and Management for Patients With Syncope. The Canadian journal of cardiology 37 3 2021 500-503 [PubMed Link] | [Full Text]
  • Ito, M.; Wang, Q.; Hao, D.; Sawada, H.; Huang, B.; Guo, L.; Daugherty, A.; Li, XA Ultrasound Monitoring of Thymus Involution in Septic Mice. Ultrasound in medicine & biology 47 3 2021 769-776 [PubMed Link] | [Full Text]
  • Davis, FM ; Tsoi, LC ; Melvin, WJ ; denDekker, A ; Wasikowski, R ; Joshi, AD ; WOLF, S.; Obi, AT ; Billi, AC ; Xing, X.; Audu, C ; Moore, BB ; Kunkel, SL ; Daugherty, A.; Lu, HS ; Gudjonsson, JE ; Gallagher, KA Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms. The Journal of experimental medicine 218 6 2021 [PubMed Link] | [Full Text]
  • Davis, FM ; Tsoi, LC ; Melvin, WJ ; denDekker, A ; Wasikowski, R ; Joshi, AD ; WOLF, S.; Obi, AT ; Billi, AC ; Xing, X.; Audu, C ; Moore, BB ; Kunkel, SL ; Daugherty, A.; Lu, HS ; Gudjonsson, JE ; Gallagher, KA Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms. The Journal of experimental medicine 218 6 2021 [PubMed Link] | [Full Text]
  • Shaw, BC ; Katsumata, Y.; Simpson, JF ; Fardo, DW ; Estus, S. Analysis of Genetic Variants Associated with Levels of Immune Modulating Proteins for Impact on Alzheimer's Disease Risk Reveal a Potential Role for SIGLEC14. Genes 12 7 2021 [PubMed Link] | [Full Text]
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