Research in Physiology

UKy Physiology Research: Cardiovascular -> Neuroscience -> Metabolic Disease -> Aging;

The Department of Physiology is proud of our strong tradition of interdisciplinary and collaborative research. Faculty members currently hold research grants from funding organizations including the National Institutes of Health, the National Science Foundation, the American Heart Association, and others.  The Department also supports NIH Training Grants and Journal Clubs.



Aging Focus Area

NameResearch Interests
Francisco H. Andrade, PhDDevelopment and Aging of Craniofacial and Respiratory Muscles
Erhard Bieberich, PhDLipid Biochemistry
Alan Daugherty, PhD, D.Sc.Cardiovascular Research Center
Steven Estus, PhDMolecular Genetics of Alzheimers Disease
Lance Johnson, PhDApoE, brain metabolism and cognition
Mariana Nikolova-Karakashian, PhDRole of Sphingolipid Signal Transduction Pathway in Animal Aging.
Donna M. Wilcock, PhDRole of Inflammation in Alzheimer’s Disease Therapeutics
Melinda E Wilson, PhDMechanisms of Estrogen Action


Cardiovascular Focus Area 

NameResearch Interests
Alan Daugherty, PhD, D.Sc.Molecular Mechanisms of Human Vascular Diseases
Kenneth S. Campbell, PhDHeart Failure Muscle Physiology Computer Modeling Biospecimens
Brian P. Delisle, PhDCardiovascular
Ming Cui Gong, PhD, MDSignal Transduction in Vascular Smooth Muscle
Scott Gordon, Ph.DMetabolism and atherosclerotic cardiovascular disease
Brian A. Jackson, PhDSignal Transduction Systems Involved in Regulation of Renal Tubular Transport 
and in Adrenal Catecholamine Synthesis and Secretion
David C. Randall, PhDAutonomic Control of Cardiovascular Function
Jonathan Satin, PhDStructure-Function Studies of Voltage-Gated Ion Channels in Heart and Nerve.

Metabolic Disease Focus Area

NameResearch Interests
Ming Cui Gong, PhD, MDSignal Transduction in Vascular Smooth Muscle
Lance Johnson, PhDApoE, brain metabolism and cognition
Mariana Nikolova-Karakashian, PhDRole of Sphingolipid Signal Transduction Pathway in Animal Aging
Bret N. Smith, PhD

Neuronal Interactions in the Mammalian Brain

Neuroscience Focus Area

NameResearch Interests

Francisco H. Andrade, PhD

Development and aging of craniofacial and respiratory muscles

Erhard Bieberich, PhD

Lipid Biochemistry

Steven Estus, PhD

Molecular Genetics of Alzheimer Disease

Gregory Frolenkov, PhD

Cellular and Molecular Mechanisms of Hearing

John Carib Gensel, PhD

Neuroinflammation in Spinal Cord and Brain Injury

Lance Johnson, PhD

ApoE, brain metabolism and cognition

Lu-Yuan Lee, PhD

Airway hypersensitivity; TRPV Channels in the Airways

Sandra J Legan, PhD

Neuroendocrine Mechanisms Mediating the Feedback Actions of Ovarian Steroids on Gonadotropin Secretion

Timothy S McClintock, PhD

Molecular Biology and Functional Genomics of Olfaction, Neural Regeneration, and Spinal Cord Injury

Alexander (Sasha) G Rabchevsky, PhD

Genetic, Biochemical and Cellular Approaches for Treatment of Spinal Cord Injury

Kathryn Saatman, PhD

Pathophysiology of Traumatic Brain Injury

Bret N. Smith, PhD

Neuronal Interactions in the Mammalian Brain

Donna M. Wilcock, PhD

Role of Inflammation in Alzheimer’s Disease Therapeutics

Melinda E Wilson, PhD

Mechanisms of Estrogen Action