Simone Crivelli

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s.crivelli@uky.edu

Physiology

Position(s):

Post-Doctoral Scholar

Affiliation(s):

Physiology

Mentor:

Erhard Bieberich

PubMed Publications:

Tripathi, P.; Zhu, Z.; Qin, H.; Elsherbini, A.; Roush, EA ; Crivelli, SM ; Spassieva, SD ; Bieberich, E. "Cross-Link/Proximity Ligation Assay for Visualization of Lipid and Protein Complexes in Lipid Rafts." Methods in molecular biology (Clifton, N.J.) 2187, (2021): 337-348. [PubMed Link] | [ Full text ]
Giovagnoni, C ; Crivelli, SM ; Losen, M ; Martinez-Martinez, P "Immunofluorescence Labeling of Lipid-Binding Proteins CERTs to Monitor Lipid Raft Dynamics." Methods in molecular biology (Clifton, N.J.) 2187, (2021): 327-335. [PubMed Link] | [ Full text ]
Elsherbini, A.; Qin, H.; Zhu, Z.; Tripathi, P.; Wang, G.; Crivelli, SM ; Spassieva, SD ; Bieberich, E. "Extracellular Vesicles Containing Ceramide-Rich Platforms: "Mobile Raft" Isolation and Analysis." Methods in molecular biology (Clifton, N.J.) 2187, (2021): 87-98. [PubMed Link] | [ Full text ]
Crivelli, SM ; van Kruining, D ; Luo, Q.; Stevens, JAA ; Giovagnoni, C ; Paulus, A ; Bauwens, M ; Berkes, D ; de Vries, HE ; Mulder, MT ; Walter, J.; Waelkens, E ; Derua, R ; Swinnen, JV ; Dehairs, J ; Mottaghy, FM ; Losen, M ; Bieberich, E.; Martinez-Martinez, P "Ceramide analog <sup>18</sup>F F-HPA-12 detects sphingolipid disbalance in the brain of Alzheimer's disease transgenic mice by functioning as a metabolic probe." Scientific reports 10, 1 (2020): 19354. [PubMed Link] | [ Full text ]
Elsherbini, A.; Qin, H.; Zhu, Z.; Tripathi, P.; Crivelli, SM ; Bieberich, E. "In vivo evidence of exosome-mediated Aβ neurotoxicity." Acta neuropathologica communications 8, 1 (2020): 100. [PubMed Link] | [ Full text ]
Tripathi, P.; Zhu, Z.; Qin, H.; Elsherbini, A.; Crivelli, SM ; Roush, E ; Wang, G.; Spassieva, SD ; Bieberich, E. "Palmitoylation of acetylated tubulin and association with ceramide-rich platforms is critical for ciliogenesis." Journal of lipid research (2020): [PubMed Link] | [ Full text ]
Elsherbini, A.; Kirov, AS ; Dinkins, MB ; Wang, G.; Qin, H.; Zhu, Z.; Tripathi, P.; Crivelli, SM ; Bieberich, E. "Association of Aβ with ceramide-enriched astrosomes mediates Aβ neurotoxicity." Acta neuropathologica communications 8, 1 (2020): 60. [PubMed Link] | [ Full text ]
Crivelli, SM ; Giovagnoni, C ; Visseren, L ; Scheithauer, AL ; de Wit, N ; Hoedt, den ; Losen, M ; Mulder, MT ; Walter, J.; de Vries, HE ; Bieberich, E.; Martinez-Martinez, P "Sphingolipids in Alzheimer's disease, how can we target them?" Advanced drug delivery reviews 159, (2020): 214-231. [PubMed Link] | [ Full text ]
Jiang, X.; Zhu, Z.; Qin, H.; Tripathi, P.; Zhong, L.; Elsherbini, A.; Karki, S.; Crivelli, SM ; Zhi, W.; Wang, G.; Spassieva, SD ; Bieberich, E. "Visualization of Ceramide-Associated Proteins in Ceramide-Rich Platforms Using a Cross-Linkable Ceramide Analog and Proximity Ligation Assays With Anti-ceramide Antibody." Frontiers in cell and developmental biology 7, (2019): 166. [PubMed Link] | [ Full text ]
Crivelli, SM ; Paulus, A ; Markus, J ; Bauwens, M ; Berkes, D ; de Vries, HE ; Mulder, MT ; Walter, J.; Mottaghy, FM ; Losen, M ; Martinez-Martinez, P "Synthesis, Radiosynthesis, and Preliminary in vitro and in vivo Evaluation of the Fluorinated Ceramide Trafficking Inhibitor (HPA-12) for Brain Applications." Journal of Alzheimer's disease : JAD 60, 3 (2017): 783-794. [PubMed Link] | [ Full text ]
Hoedt, den ; Janssen, CIF ; Astarita, G.; Piomelli, D.; Leijten, FPJ ; Crivelli, SM ; Verhoeven, AJM ; de Vries, HE ; Walter, J.; Martinez-Martinez, P ; Sijbrands, EJG ; Kiliaan, AJ ; Mulder, MT "Pleiotropic Effect of Human ApoE4 on Cerebral Ceramide and Saturated Fatty Acid Levels." Journal of Alzheimer's disease : JAD 60, 3 (2017): 769-781. [PubMed Link] | [ Full text ]